Arthritis is a major public health problem and one of the leading causes of disability worldwide.  Genetic and environmental factors contribute to the onset of degenerative joint diseases such as osteoarthritis and rheumatoid arthritis. The heterogeneity of these chronic diseases presents therapeutic challenges and joint replacement surgery remains the only viable strategy to restore joint function in advanced disease. Research led by Dr. Kim Mix aims to elucidate the molecular and cellular events driving cartilage degradation and synovial inflammation in arthritis. Learn more about this research here.