The Earls Laboratory is interested in developmental processes that occur in the adult brain. Rather than treat the adult brain as a monolith, we study how the brain continues to execute programmed molecular changes well into adulthood. Our studies are focused on the hippocampus, a region of the brain that is important for learning and memory, and which ages according to a unique molecular program. We use electrophysiology, behavior, genetics, molecular biology and biochemistry to determine the rules that govern hippocampal maturation during early adulthood. These studies have important implications for understanding cognitive diseases, many of which emerge only within specific stages of adulthood. By studying normative early aging, we can better understand the age-dependent cognitive symptoms of diseases such as schizophrenia. More info coming soon.